Clinical Professor
M_MED-CORE-NEPH-GEN
+1 415 353-1322
I have been at UCSF since 1975 and on the faculty of the Department of Medicine in the division of Nephrology since 1976 and have been involved with the transplant service in patient care and clinical trials with novel immunosuppression drugs
Publications
Dysregulated Bone Marrow Contributes to Glomerular Injury through Soluble Factors.
Journal of the American Society of Nephrology : JASN
Clinical events and healthcare resource utilization associated with neutropenia and leukopenia among adult kidney transplant recipients receiving valganciclovir.
World journal of transplantation
Healthcare resource use and clinical events associated with neutropenia among adult kidney transplant recipients receiving valganciclovir or ganciclovir prophylaxis: a matched case-control cohort study.
Current medical research and opinion
Antiplasma cell antibodies: A new era of human leukocyte antigen antibody control in solid organ transplantation.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Anti-HLA serologic response to CD38-targeting desensitization therapy is challenged by peripheral memory B cells in highly sensitized kidney transplant candidates.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Poised for Innovation: Considerations for End Points for New Drug Development in Kidney Transplantation.
Journal of the American Society of Nephrology : JASN
Long-term Safety in Epstein-Barr Virus-Seropositive Kidney-only Transplant Recipients Treated With Belatacept in Clinical Practice: Final Study Results From the ENLiST Registry.
Transplantation direct
The hepatocyte growth factor mimetic, ANG-3777, in kidney transplant recipients with delayed graft function: results from a randomized phase 3 trial.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Isatuximab Monotherapy for Desensitization in Highly Sensitized Patients Awaiting Kidney Transplant.
Journal of the American Society of Nephrology : JASN
State of the art in childhood nephrotic syndrome: concrete discoveries and unmet needs.
Frontiers in immunology
Open letter to Bristol Myers Squibb: belatacept; we aren't done yet.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Race-free estimated glomerular filtration rate equation in kidney transplant recipients: development and validation study.
BMJ (Clinical research ed.)
Perturbations in podocyte transcriptome and biological pathways induced by FSGS associated circulating factors.
Annals of translational medicine
Human Bone Marrow Plasma Cell Atlas: Maturation and Survival Pathways Unraveled by Single Cell Analyses.
bioRxiv : the preprint server for biology
Burden of neutropenia and leukopenia among adult kidney transplant recipients: A systematic literature review of observational studies.
Transplant infectious disease : an official journal of the Transplantation Society
Obinutuzumab Effectively Depletes Key B-cell Subsets in Blood and Tissue in End-stage Renal Disease Patients.
Transplantation direct
Infliximab Induction Lacks Efficacy and Increases BK Virus Infection in Deceased Donor Kidney Transplant Recipients.
Journal of the American Society of Nephrology : JASN
Outcomes among CMV-mismatched and highly sensitized kidney transplants recipients who develop neutropenia.
Clinical transplantation
IL-6 and TNFa Drive Extensive Proliferation of Human Tregs Without Compromising Their Lineage Stability or Function.
Frontiers in immunology
Conversion from Calcineurin Inhibitor to Belatacept-based Maintenance Immunosuppression in Renal Transplant Recipients: a Randomized Phase 3b Trial.
Journal of the American Society of Nephrology : JASN
Tests for the non-invasive diagnosis of kidney transplant rejection should be evaluated by kidney transplant programs.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
A Comparison of Ex Vivo Expanded Human Regulatory T Cells Using Allogeneic Stimulated B Cells or Monocyte-Derived Dendritic Cells.
Frontiers in immunology
Interleukin-6 Blockade with Tocilizumab Increases Tregs and Reduces T Effector Cytokines in Renal Graft Inflammation: A Randomized Controlled Trial.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Single-Cell RNA Sequencing of Tocilizumab-Treated Peripheral Blood Mononuclear Cells as an in vitro Model of Inflammation.
Frontiers in genetics
Optimization of de novo belatacept-based immunosuppression administered to renal transplant recipients.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Phase 3 trial Design of the Hepatocyte Growth Factor Mimetic ANG-3777 in Renal Transplant Recipients With Delayed Graft Function.
Kidney international reports
The impact of belatacept on the phenotypic heterogeneity of renal T cell-mediated alloimmune response: the critical role of maintenance treatment and inflammatory load.
Clinical transplantation
Single-cell RNA sequencing of Tocilizumab-treated peripheral blood mononuclear cells as an in vitro model of inflammation.
bioRxiv : the preprint server for biology
A urine score for noninvasive accurate diagnosis and prediction of kidney transplant rejection.
Science translational medicine
Further Evidence That the Soluble Urokinase Plasminogen Activator Receptor Does Not Directly Injure Mice or Human Podocytes.
Transplantation
Assessment of 19 Genes and Validation of CRM Gene Panel for Quantitative Transcriptional Analysis of Molecular Rejection and Inflammation in Archival Kidney Transplant Biopsies.
Frontiers in medicine
A randomized, phase 1b study of the pharmacokinetics, pharmacodynamics, safety, and tolerability of bleselumab, a fully human, anti-CD40 monoclonal antibody, in kidney transplantation.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Evidence-based practice: Guidance for using everolimus in combination with low-exposure calcineurin inhibitors as initial immunosuppression in kidney transplant patients.
Transplantation reviews (Orlando, Fla.)
Safety, pharmacokinetics, and pharmacodynamic activity of obinutuzumab, a type 2 anti-CD20 monoclonal antibody for the desensitization of candidates for renal transplant.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Two-year outcomes in de novo renal transplant recipients receiving everolimus-facilitated calcineurin inhibitor reduction regimen from the TRANSFORM study.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Characterizing pre-transplant and post-transplant kidney rejection risk by B cell immune repertoire sequencing.
Nature communications
Identifying a potential biomarker for primary focal segmental glomerulosclerosis and its association with recurrence after transplantation.
Clinical transplantation
Efficacy and Safety of a Tofacitinib-based Immunosuppressive Regimen After Kidney Transplantation: Results From a Long-term Extension Trial.
Transplantation direct
Nuclear Factor of Activated T Cell-regulated Cytokine Gene Expression for Adjustment of Tacrolimus in Kidney Transplant Recipients: A Randomized Controlled Pilot Trial.
Transplantation direct
A randomized, phase 2 study of ASP0113, a DNA-based vaccine, for the prevention of CMV in CMV-seronegative kidney transplant recipients receiving a kidney from a CMV-seropositive donor.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Everolimus with Reduced Calcineurin Inhibitor Exposure in Renal Transplantation.
Journal of the American Society of Nephrology : JASN
Outcomes at 7 years post-transplant in black vs nonblack kidney transplant recipients administered belatacept or cyclosporine in BENEFIT and BENEFIT-EXT.
Clinical transplantation
Targeted Transcriptional Profiling of Kidney Transplant Biopsies.
Kidney international reports
Mycophenolate Mofetil Withdrawal With Conversion to Everolimus to Treat BK Virus Infection in Kidney Transplant Recipients.
Transplantation proceedings
Ten-year outcomes in a randomized phase II study of kidney transplant recipients administered belatacept 4-weekly or 8-weekly.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Polyclonal Regulatory T Cell Therapy for Control of Inflammation in Kidney Transplants.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Retrospective evaluation of the efficacy and safety of belatacept with thymoglobulin induction and maintenance everolimus: A single-center clinical experience.
Clinical transplantation
Transplant trials with Tregs: perils and promises.
The Journal of clinical investigation
B Cell Receptor Genes Associated With Tolerance Identify a Cohort of Immunosuppressed Patients With Improved Renal Allograft Graft Function.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
A Phase 2, Double-Blind, Placebo-Controlled, Randomized Study of Fresolimumab in Patients With Steroid-Resistant Primary Focal Segmental Glomerulosclerosis.
Kidney international reports
Belatacept: the challenges with transformational drugs.
Translational andrology and urology
Early post-transplant conversion from tacrolimus to belatacept for prolonged delayed graft function improves renal function in kidney transplant recipients.
Clinical transplantation
Safety and Efficacy Outcomes 3 Years After Switching to Belatacept From a Calcineurin Inhibitor in Kidney Transplant Recipients: Results From a Phase 2 Randomized Trial.
American journal of kidney diseases : the official journal of the National Kidney Foundation
Current status of costimulatory blockade in renal transplantation.
Current opinion in nephrology and hypertension
Costimulatory Blockade and Use of mTOR Inhibitors: Avoiding Injury Part 2.
Advances in chronic kidney disease
Steroid-Responsive Acute Rejection Should Not Be the End Point for Immunosuppressive Trials.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Belatacept and Long-Term Outcomes in Kidney Transplantation.
The New England journal of medicine
An Update on Calcineurin Inhibitor-Free Regimens: The Need Persists, but the Landscape has Changed.
Transplantation
Belatacept and Long-Term Outcomes in Kidney Transplantation.
The New England journal of medicine
Evaluation of the effect of tofacitinib exposure on outcomes in kidney transplant patients.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
The kSORT assay to detect renal transplant patients at high risk for acute rejection: results of the multicenter AART study.
PLoS medicine
Role of podocyte B7-1 in diabetic nephropathy.
Journal of the American Society of Nephrology : JASN
Clinical aspects: focusing on key unique organ-specific issues of renal transplantation.
Cold Spring Harbor perspectives in medicine
Long-term belatacept exposure maintains efficacy and safety at 5 years: results from the long-term extension of the BENEFIT study.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Tofacitinib in kidney transplantation.
Expert opinion on investigational drugs
Report of the second joint meeting of ESOT and AST: current pipelines in biotech and pharma.
Transplant international : official journal of the European Society for Organ Transplantation
Native renal function after combined liver-kidney transplant for type 1 hepatorenal syndrome: initial report on the use of postoperative Technetium-99 m-mercaptoacetyltriglycine scans.
Transplant international : official journal of the European Society for Organ Transplantation
Ciprofloxacin prophylaxis in kidney transplant recipients reduces BK virus infection at 3 months but not at 1 year.
Transplantation
Belatacept in kidney transplantation.
Current opinion in organ transplantation
Polyomavirus BK replication in de novo kidney transplant patients receiving tacrolimus or cyclosporine: a prospective, randomized, multicenter study.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Belatacept for prevention of acute rejection in adult patients who have had a kidney transplant: an update.
Biologics : targets & therapy
Altered balance between effector T cells and FOXP3+ HELIOS+ regulatory T cells after thymoglobulin induction in kidney transplant recipients.
Transplant international : official journal of the European Society for Organ Transplantation
Improvement in renal function in kidney transplant recipients switched from cyclosporine or tacrolimus to belatacept: 2-year results from the long-term extension of a phase II study.
Transplant international : official journal of the European Society for Organ Transplantation
Randomized phase 2b trial of tofacitinib (CP-690,550) in de novo kidney transplant patients: efficacy, renal function and safety at 1 year.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Are calcineurin inhibitors-free regimens ready for prime time?
Kidney international
Beyond belatacept: praise and progress for the FDA.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Targeting JAK3 in kidney transplantation: current status and future options.
Current opinion in organ transplantation
C4d/CD34 double-immunofluorescence staining of renal allograft biopsies for assessing peritubular capillary C4d positivity.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Three-year outcomes from BENEFIT, a randomized, active-controlled, parallel-group study in adult kidney transplant recipients.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Belatacept-versus cyclosporine-based immunosuppression in renal transplant recipients with pre-existing diabetes.
Clinical journal of the American Society of Nephrology : CJASN
Belatacept.
Nature reviews. Drug discovery
Challenges and opportunities in targeting the costimulation pathway in solid organ transplantation.
Seminars in immunology
Novel strategies in immunosuppression: issues in perspective.
Transplantation
Sotrastaurin, a novel small molecule inhibiting protein-kinase C: randomized phase II study in renal transplant recipients.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
A phase 1, single-dose study of fresolimumab, an anti-TGF-ß antibody, in treatment-resistant primary focal segmental glomerulosclerosis.
Kidney international
Response to questions regarding the design and results of the IMPACT trial.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
An integrated safety profile analysis of belatacept in kidney transplant recipients.
Transplantation
How the development of new biological agents may help minimize immunosuppression in kidney transplantation: the impact of belatacept.
Current opinion in organ transplantation
Immunosuppression with belatacept-based, corticosteroid-avoiding regimens in de novo kidney transplant recipients.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Switching from calcineurin inhibitor-based regimens to a belatacept-based regimen in renal transplant recipients: a randomized phase II study.
Clinical journal of the American Society of Nephrology : CJASN
Associations of pretransplant diabetes mellitus, new-onset diabetes after transplant, and acute rejection with transplant outcomes: an analysis of the Organ Procurement and Transplant Network/United Network for Organ Sharing (OPTN/UNOS) database.
American journal of kidney diseases : the official journal of the National Kidney Foundation
Islet transplantation in type 1 diabetics using an immunosuppressive protocol based on the anti-LFA-1 antibody efalizumab.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Five-year safety and efficacy of belatacept in renal transplantation.
Journal of the American Society of Nephrology : JASN
The efficacy and safety of 200 days valganciclovir cytomegalovirus prophylaxis in high-risk kidney transplant recipients.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
A phase III study of belatacept versus cyclosporine in kidney transplants from extended criteria donors (BENEFIT-EXT study).
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
A phase III study of belatacept-based immunosuppression regimens versus cyclosporine in renal transplant recipients (BENEFIT study).
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Kidney transplantation at UCSF: 8,300 transplants and onward.
Clinical transplants
Novel B cell therapeutic targets in transplantation and immune-mediated glomerular diseases.
Clinical journal of the American Society of Nephrology : CJASN
KDIGO clinical practice guideline for the care of kidney transplant recipients: a summary.
Kidney international
Calcineurin-inhibitor-free immunosuppression based on the JAK inhibitor CP-690,550: a pilot study in de novo kidney allograft recipients.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Kidney transplantation: the ideal immunosuppression regimen.
Advances in chronic kidney disease
Transplantation: To convert or not to convert: lessons from the CONVERT trial.
Nature reviews. Nephrology
The AST's perspective on the proposed kidney allocation system.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
The challenge of achieving target drug concentrations in clinical trials: experience from the Symphony study.
Transplantation
Long-term renal function and cardiovascular disease risk in obese kidney donors.
Clinical journal of the American Society of Nephrology : CJASN
Evolving trends in induction therapy.
Transplantation reviews (Orlando, Fla.)
Assessment of belatacept-mediated costimulation blockade through evaluation of CD80/86-receptor saturation.
Transplantation
Mycophenolic acid exposure after administration of mycophenolate mofetil in the presence and absence of cyclosporin in renal transplant recipients.
Clinical pharmacokinetics
The effect of costimulatory and interleukin 2 receptor blockade on regulatory T cells in renal transplantation.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
What's next in the pipeline.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Tolerance versus immunosuppression: a perspective.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Association of four DNA polymorphisms with acute rejection after kidney transplantation.
Transplant international : official journal of the European Society for Organ Transplantation
Open letter to the FDA: new drug trials must be relevant.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
A randomized, multicenter study of steroid avoidance, early steroid withdrawal or standard steroid therapy in kidney transplant recipients.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Costimulation blockade in autoimmunity and transplantation.
The Journal of allergy and clinical immunology
Cyclosporine sparing with mycophenolate mofetil, daclizumab and corticosteroids in renal allograft recipients: The CAESAR Study. Am J Transplant 7, 560-570, 2007.
Clinical journal of the American Society of Nephrology : CJASN
Proteomics of plasma and urine in primary nephrotic syndrome in children.
Contributions to nephrology
Results of an international, randomized trial comparing glucose metabolism disorders and outcome with cyclosporine versus tacrolimus. Am J Transplant 7 1506-1514, 2007.
Clinical journal of the American Society of Nephrology : CJASN
Rituximab failed to improve nephrotic syndrome in renal transplant patients with recurrent focal segmental glomerulosclerosis.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
A phase I/II randomized open-label multicenter trial of efalizumab, a humanized anti-CD11a, anti-LFA-1 in renal transplantation.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Novel immunosuppression: small molecules and biologics.
Seminars in nephrology
Pharmacokinetics, safety, and efficacy of mycophenolate mofetil in combination with sirolimus or ciclosporin in renal transplant patients.
British journal of clinical pharmacology
Costimulation blockade--what will the future bring?
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
Results of an international, randomized trial comparing glucose metabolism disorders and outcome with cyclosporine versus tacrolimus.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Sirolimus: defining nephrotoxicity in the renal transplant recipient.
Clinical journal of the American Society of Nephrology : CJASN
Active focal segmental glomerulosclerosis is associated with massive oxidation of plasma albumin.
Journal of the American Society of Nephrology : JASN
Cyclosporine sparing with mycophenolate mofetil, daclizumab and corticosteroids in renal allograft recipients: the CAESAR Study.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
T cell costimulation: a rational target in the therapeutic armamentarium for autoimmune diseases and transplantation.
Annual review of medicine
Living donor kidney transplant recipients and clinical trials: participation profiles and impact on post-transplant care.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Immunosuppression: today, tomorrow, and withdrawal.
Seminars in liver disease
Interleukin-2 receptor antagonist induction in modern immunosuppression regimens for renal transplant recipients.
Transplant international : official journal of the European Society for Organ Transplantation
Antibodies come back to the forefront in transplantation.
Clinical journal of the American Society of Nephrology : CJASN
A multicenter, prospective study of C2-monitored cyclosporine microemulsion in a U.S. population of de novo renal transplant recipients.
Transplantation
Current use and future trends in induction therapy.
Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia
Rapidly developing nephrocalcinosis in a patient with end-stage liver disease who received a domino liver transplant from a patient with known congenital oxalosis.
Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine
Costimulation blockade with belatacept in renal transplantation.
The New England journal of medicine
A drug of the past, a lesson for the future.
Pediatric transplantation
Guidelines for the treatment and management of new-onset diabetes after transplantation.
Clinical transplantation
New insights into the pathogenesis and the therapy of recurrent focal glomerulosclerosis.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Prospective, multicenter, randomized trial to compare incidence of new-onset diabetes mellitus and glucose metabolism in patients receiving cyclosporine microemulsion versus tacrolimus after de novo kidney transplantation.
Transplantation proceedings
An open-label, pilot study evaluating the safety and efficacy of converting from calcineurin inhibitors to sirolimus in established renal allograft recipients with moderate renal insufficiency.
Clinical transplantation
Rationale and design of the DIRECT study: a comparative assessment of the hyperglycemic effects of tacrolimus and cyclosporine following renal transplantation.
Contemporary clinical trials
A multicenter pilot study of early (4-day) steroid cessation in renal transplant recipients under simulect, tacrolimus and sirolimus.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Chronic induction. What's new in the pipeline.
Contributions to nephrology
BK nephropathy in kidney transplant recipients treated with a calcineurin inhibitor-free immunosuppression regimen.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Interleukin-2 receptor antagonists and aggressive steroid minimization strategies for kidney transplant patients.
Transplant international : official journal of the European Society for Organ Transplantation
Infliximab in the treatment of steroid-dependent ulcerative colitis.
European review for medical and pharmacological sciences
A decade of progress in kidney transplantation.
Transplantation
Recurrent focal glomerulosclerosis in the era of genetics of podocyte proteins: theory and therapy.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
Optimizing the use of cyclosporine (Neoral) for recipients of living donor kidneys.
Transplantation proceedings
Pharmacokinetics of daclizumab and mycophenolate mofetil with cyclosporine and steroids in renal transplantation.
Clinical transplantation
CD69 expression on peripheral CD8 T cells correlates with acute rejection in renal transplant recipients.
Transplantation
Immunosuppression minimization: current and future trends in transplant immunosuppression.
Journal of the American Society of Nephrology : JASN
Prevalence and management of anemia in renal transplant recipients: a European survey.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
De novo use of sirolimus in immunosuppression regimens in kidney and kidney-pancreas transplantation at the University of California, San Francisco.
Transplantation proceedings
Multicenter randomized prospective trial of steroid withdrawal in renal transplant recipients receiving basiliximab, cyclosporine microemulsion and mycophenolate mofetil.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
New monoclonal antibodies in renal transplantation.
Minerva urologica e nefrologica = The Italian journal of urology and nephrology
Pharmacokinetic and pharmacodynamic studies of one or two doses of daclizumab in renal transplantation.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
What's in the pipeline? New immunosuppressive drugs in transplantation.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
A long-term comparison of tacrolimus (FK506) and cyclosporine in kidney transplantation: evidence for improved allograft survival at five years.
Transplantation
Effect of calcineurin inhibitor therapy on P-gp expression and function in lymphocytes of renal transplant patients: a preliminary evaluation.
Journal of clinical pharmacology
Interleukin-2 receptor monoclonal antibodies in renal transplantation: current use and emerging regimens.
Transplantation proceedings
Results of 3-year phase III clinical trials with daclizumab prophylaxis for prevention of acute rejection after renal transplantation.
Transplantation
Is complete avoidance of calcineurin inhibitors or steroids now possible? Importance of patient selection and choice of regimen.
Transplantation proceedings
Multicenter trial exploring calcineurin inhibitors avoidance in renal transplantation.
Transplantation
Rapid steroid withdrawal versus standard steroid therapy in patients treated with basiliximab, cyclosporine, and mycophenolate mofetil for the prevention of acute rejection in renal transplantation.
Transplantation proceedings
Tacrolimus (FK 506) in kidney transplantation: five-year survival results of the U.S. multicenter, randomized, comparative trial.
Transplantation proceedings
The role of newer monoclonal antibodies in renal transplantation.
Transplantation proceedings
Phase I trial of HuM291, a humanized anti-CD3 antibody, in patients receiving renal allografts from living donors.
Transplantation
A calcineurin inhibitor-sparing regimen with sirolimus, mycophenolate mofetil, and anti-CD25 mAb provides effective immunosuppression in kidney transplant recipients with delayed or impaired graft function.
Clinical transplantation
Coadministration of tacrolimus and mycophenolate mofetil in stable kidney transplant patients: pharmacokinetics and tolerability.
Journal of clinical pharmacology
The role of daclizumab in balancing resources for inpatient and outpatient transplant services.
Progress in transplantation (Aliso Viejo, Calif.)
Daclizumab prevents acute rejection and improves patient survival post transplantation: 1 year pooled analysis.
Transplant international : official journal of the European Society for Organ Transplantation
Recurrent and de novo glomerular disease after renal transplantation: a report from Renal Allograft Disease Registry (RADR).
Transplantation
Daclizumab: novel biologic immunoprophylaxis for prevention of acute rejection in renal transplantation.
Transplantation proceedings
Potential of daclizumab in solid organ transplantation.
BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy
Can antibody prophylaxis allow sparing of other immunosuppressives?
Transplantation proceedings
Recurrent and de novo glomerular disease after renal transplantation: a report from renal allograft disease registry.
Transplantation proceedings
Review of transplantation--1999.
Clinical transplants
Daclizumab: outcome of phase III trials and mechanism of action. Double Therapy and the Triple Therapy Study Groups.
Transplantation proceedings
Interleukin-2-receptor blockade with daclizumab to prevent acute rejection in renal transplantation. Daclizumab Triple Therapy Study Group.
The New England journal of medicine
Selection strategies for successful utilization of less than 15.kg pediatric donor kidneys.
Transplantation proceedings
Anaesthetic management of children with type II and III Gaucher disease.
Minerva pediatrica
FK 506 in kidney transplantation: results of the U.S.A. randomized comparative phase III study. The FK 506 Kidney Transplant Study Group.
Transplantation proceedings
A phase I trial of humanized anti-interleukin 2 receptor antibody in renal transplantation.
Transplantation
Circulating factor associated with increased glomerular permeability to albumin in recurrent focal segmental glomerulosclerosis.
The New England journal of medicine
In vivo (phase I) trial and in vitro efficacy of humanized anti-Tac for the prevention of rejection in renal transplant recipients.
Transplantation proceedings
Pentoxifylline does not prevent the cytokine-induced first dose reaction following OKT3--a randomized, double-blind placebo-controlled study.
Transplantation
Fibrosing cholestatic hepatitis in renal transplant recipients.
Transplantation
Histopathological concordance of paired renal allograft biopsy cores. Effect on the diagnosis and management of acute rejection.
Transplantation
Long-term outcome in kidney transplant patients with hepatitis C (HCV) infection.
Clinical transplantation
Phase II FK 506 multicenter concentration control study: one-year follow-up.
Transplantation proceedings
The risk of transmission of hepatitis B from HBsAg(-), HBcAb(+), HBIgM(-) organ donors.
Transplantation
Plasmapheresis reduces proteinuria and serum capacity to injure glomeruli in patients with recurrent focal glomerulosclerosis.
American journal of kidney diseases : the official journal of the National Kidney Foundation
Pentoxifylline reduces the first-dose reactions following OKT3.
Transplantation proceedings
Hepatitis C--its prevalence in end-stage renal failure patients and clinical course after kidney transplantation.
Transplantation
Recurrent focal glomerulosclerosis: natural history and response to therapy.
The American journal of medicine
Hepatitis C virus in cadaver organ donors: prevalence and risk of transmission to transplant recipients.
Transplantation proceedings
Effect of cyclosporine on the clinical course of HBsAg-positive renal transplant patients.
Transplantation proceedings
Improved results with combined donor-specific transfusion (DST) and sequential therapy protocol.
Transplantation proceedings
Inability of cyclosporine to completely prevent the recurrence of focal glomerulosclerosis after kidney transplantation.
Transplantation
Immunologic alterations induced by donor-specific transfusion.
Transplantation proceedings
Successful management of the highly sensitized renal allograft recipient.
Transplantation proceedings
The incidence and impact of herpes simplex virus infections in the first month following renal transplantation.
Transplantation proceedings
Cyclosporine provides better success rates for both higher- and lower-risk cadaveric kidney transplant recipients.
Transplantation proceedings
How to improve results for second renal allografts.
Transplantation proceedings
Is cyclosporine effective in preventing recurrence of immune-mediated glomerular disease after renal transplantation?
Transplantation proceedings
Posttransplant renal rejection: comparison of quantitative scintigraphy, US, and MR imaging.
Radiology
Donor-specific blood transfusions versus cyclosporine--the DST story.
Transplantation proceedings
Has cyclosporine really relegated pretransplant blood transfusions to therapeutic obsolescence?
Transplantation proceedings
Observations relating to the incidence of the acquired immune deficiency syndrome and other possibly associated conditions in a large population of renal transplant recipients.
Transplantation proceedings
Sonography in the diagnosis of acute renal allograft rejection and cyclosporine nephrotoxicity.
AJR. American journal of roentgenology
The beneficial effect of pretransplant blood transfusions in cyclosporine-treated cadaver renal allograft recipients.
Transplantation
The clinical course of IgA-nephropathy and Henoch-Schönlein purpura following renal transplantation.
Transplantation
Clinical management of immunosuppressive therapy for cyclosporine-treated recipients of cadaver kidney transplants at one to six months.
Transplantation proceedings
Is a "low" dose of prednisone better than a "high" dose at the time of renal transplantation?
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas
A seven-year experience with donor-specific blood transfusions. Results and considerations for maximum efficacy.
Transplantation
Pharmacokinetics of sulfisoxazole in renal transplant patients.
Antimicrobial agents and chemotherapy
Dramatic improvement in the success rate for renal transplants in diabetic recipients with donor-specific transfusions.
Transplantation
Peptic ulcer disease in kidney transplant recipients.
American journal of surgery
Parathyroid and bone response of the diabetic patient to uremia.
Kidney international
Long-term renal function in kidney donors. Sustained compensatory hyperfiltration with no adverse effects.
Transplantation
The role of blood transfusions in renal transplantation.
The Urologic clinics of North America
Furosemide assays and disposition in healthy volunteers and renal transplant patients.
Federation proceedings
Urinary kallikrein excretion after renal transplantation: relationship to hypertension, graft source, and renal function.
The American journal of medicine
Blood transfusions before and on the day of transplantation: effects on cadaver graft survival.
Transplantation proceedings
Update of the University of California at San Francisco experience with donor-specific blood transfusions.
Transplantation proceedings
Blood transfusions and kidney transplantation.
Archives of internal medicine
Prednisone and prednisolone bioavailability in renal transplant patients.
Kidney international
Prognostic features of early renal transplant rejections.
American journal of kidney diseases : the official journal of the National Kidney Foundation
An alternative to cadaver kidney transplants for patients with insulin-dependent diabetes mellitus.
Transplantation
Incidence, characteristics, and outcome of recipients sensitized after donor-specific blood transfusions.
Transplantation
Improved graft survival following donor-specific blood transfusions.
Transplantation proceedings
Prevention of prednisone-induced negative nitrogen balance. Effect of dietary modification on urea generation rate in patients on hemodialysis receiving high-dose glucocorticoids.
Annals of internal medicine
1,500 renal transplants at one center: evolution of a strategy for optimal success.
American journal of surgery
Furosemide kinetics and dynamics after kidney transplant.
Clinical pharmacology and therapeutics
Recurrent systemic lupus erythematosus involving renal allografts.
Annals of internal medicine
Graft survival with high levels of cytotoxic antibodies.
Transplantation proceedings
Improved graft survival with donor-specific transfusion pretreatment.
Transplantation proceedings
Pretreatment with donor-specific blood transfusions in related recipients with high MLC.
Transplantation proceedings
Prednisolone disposition in cushingoid and noncushingoid kidney transplant patients.
The Journal of clinical endocrinology and metabolism
Improved outcome following renal transplantation with reduction in the immunosuppression therapy for rejection episodes.
The American journal of medicine
The role of hypertension in hemodialysis-associated atherosclerosis.
The American journal of medicine
Post-transplantation pyelonephritis: factors producing low patient and transplant morbidity.
The Journal of urology
Deliberate donor-specific blood transfusions prior to living related renal transplantation. A new approach.
Annals of surgery
The organization of a successful donor-specific transfusion protocol in related recipients with high MLC.
Proceedings of the Clinical Dialysis and Transplant Forum
Donor-specific blood transfusions in HLA-D-disparate one-haplotype-related allografts.
Transplantation proceedings
The transplanted kidney as a source of hepatitis B infection.
Annals of internal medicine
Comparative study of albumin solution and cryoprecipitated plasma for renal preservation: a preliminary report.
Transplantation proceedings
HLA-D antigen disparity and HLA-DRw antibodies in intrafamilial renal allograft survival.
Transplantation proceedings
The influence of donor age on graft survival.
American journal of surgery
Pretransplant cytotoxic antibodies do not segregate kidney transplant recipients into responder and non-responder groups.
Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association
Immunologic factors determining survival of cadaver-kidney transplants. The effect of HLA serotyping, cytotoxic antibodies and blood transfusions on graft survival.
The New England journal of medicine
Leukocyte migration inhibitory factor (LIF) as an indicator of presensitization and allograft survival.
Transplantation proceedings
A ten year experience with cadaver kidney preservation using cryoprecipitated plasma.
American journal of surgery
Cadaver kidney transplantation provided from one center within a large geographical region.
Transactions - American Society for Artificial Internal Organs
The effect of hypothermic pulsatile perfusion on glomerular epithelial surface structures studied by scanning electron microscopy.
Transactions - American Society for Artificial Internal Organs
Hepatitis-B reactivation after renal transplantation.
Lancet (London, England)
Renal transplantation in systemic lupus erythematosus.
Proceedings of the Clinical Dialysis and Transplant Forum
Renal vein renin in hypertension. Diagnostic and therapeutic implications.
Le Journal medical libanais. The Lebanese medical journal
Tumorous hyperparathyroidism in hypophosphatemic vitamin D--resistant rickets.
Le Journal medical libanais. The Lebanese medical journal