Zoltan Laszik, MD, PhD

Prof of Clinical Pathology
Pathology
+1 415 502-8230
Publications: 

Multimodal Molecular Imaging Reveals Tissue-Based T Cell Activation and Viral RNA Persistence for Up to 2 Years Following COVID-19.

medRxiv : the preprint server for health sciences

Peluso MJ, Ryder D, Flavell R, Wang Y, Levi J, LaFranchi BH, Deveau TM, Buck AM, Munter SE, Asare KA, Aslam M, Koch W, Szabo G, Hoh R, Deswal M, Rodriguez A, Buitrago M, Tai V, Shrestha U, Lu S, Goldberg SA, Dalhuisen T, Durstenfeld MS, Hsue PY, Kelly JD, Kumar N, Martin JN, Gambir A, Somsouk M, Seo Y, Deeks SG, Laszik ZG, VanBrocklin HF, Henrich TJ

Non-full house membranous lupus nephritis represents a clinically distinct subset.

Kidney360

Ye J, Croom N, Troxell ML, Kambham N, Zuckerman JE, Andeen N, Dall'Era M, Hsu R, Walavalkar V, Laszik ZG, Urisman A

A reference tissue atlas for the human kidney.

Science advances

Hansen J, Sealfon R, Menon R, Eadon MT, Lake BB, Steck B, Anjani K, Parikh S, Sigdel TK, Zhang G, Velickovic D, Barwinska D, Alexandrov T, Dobi D, Rashmi P, Otto EA, Rivera M, Rose MP, Anderton CR, Shapiro JP, Pamreddy A, Winfree S, Xiong Y, He Y, de Boer IH, Hodgin JB, Barisoni L, Naik AS, Sharma K, Sarwal MM, Zhang K, Himmelfarb J, Rovin B, El-Achkar TM, Laszik Z, He JC, Dagher PC, Valerius MT, Jain S, Satlin LM, Troyanskaya OG, Kretzler M, Iyengar R, Azeloglu EU, Kidney Precision Medicine Project

Rationale and design of the Kidney Precision Medicine Project.

Kidney international

de Boer IH, Alpers CE, Azeloglu EU, Balis UGJ, Barasch JM, Barisoni L, Blank KN, Bomback AS, Brown K, Dagher PC, Dighe AL, Eadon MT, El-Achkar TM, Gaut JP, Hacohen N, He Y, Hodgin JB, Jain S, Kellum JA, Kiryluk K, Knight R, Laszik ZG, Lienczewski C, Mariani LH, McClelland RL, Menez S, Moledina DG, Mooney SD, O'Toole JF, Palevsky PM, Parikh CR, Poggio ED, Rosas SE, Rosengart MR, Sarwal MM, Schaub JA, Sedor JR, Sharma K, Steck B, Toto RD, Troyanskaya OG, Tuttle KR, Vazquez MA, Waikar SS, Williams K, Wilson FP, Zhang K, Iyengar R, Kretzler M, Himmelfarb J

Interleukin-6 Blockade with Tocilizumab Increases Tregs and Reduces T Effector Cytokines in Renal Graft Inflammation: A Randomized Controlled Trial.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Chandran S, Leung J, Hu C, Laszik ZG, Tang Q, Vincenti FG

A Multimodal and Integrated Approach to Interrogate Human Kidney Biopsies with Rigor and Reproducibility: Guidelines from the Kidney Precision Medicine Project.

Physiological genomics

El-Achkar TM, Eadon MT, Menon R, Lake BB, Sigdel TK, Alexandrov T, Parikh S, Zhang G, Dobib D, Dunn KW, Otto EA, Anderton CR, Carson JM, Luo J, Park C, Hamidi H, Zhou J, Hoover P, Schroeder A, Joanes M, Azeloglu EU, Sealfon R, Winfree S, Steck B, He Y, D'Agati VD, Iyengar R, Troyanskaya OG, Barisoni L, Gaut J, Zhang K, Laszik Z, Rovin B, Dagher PC, Sharma K, Sarwal M, Hodgin JB, Alpers CE, Kretzer M, Jain S, The Kidney Precision Medicine Project F

Progression of proliferative glomerulonephritis with monoclonal IgG deposits in pediatric patients.

Pediatric nephrology (Berlin, Germany)

Miller P, Xiao AY, Kung VL, Sibley RK, Higgins JP, Kambham N, Charu V, Lenihan C, Uber AM, Talley EM, Arora N, Walavalkar V, Laszik ZG, Nast CC, Troxell ML

Novel In Situ Hybridization and Multiplex Immunofluorescence Technology Combined With Whole-slide Digital Image Analysis in Kidney Transplantation.

The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society

Junger H, Dobi D, Chen A, Lee L, Vasquez JJ, Tang Q, Laszik ZG

A virtual crossmatch based strategy facilitates sharing of deceased donor kidneys for highly sensitized recipients.

Transplantation

Roll GR, Webber AB, Gae DH, Laszik Z, Tavakol M, Mayen L, Cunniffe K, Syed S, Hirose R, Freise C, Feng S, Roberts JP, Ascher NL, Stock PG, Rajalingam R

Further Evidence That the Soluble Urokinase Plasminogen Activator Receptor Does Not Directly Injure Mice or Human Podocytes.

Transplantation

Harel E, Shoji J, Abraham V, Miller L, Laszik ZG, King A, Dobi D, Szabo G, Hann B, Sarwal MM, Craik CS, Vincenti F

CD32-RNA Co-localizes with HIV-RNA in CD3+ Cells Found within Gut Tissues from Viremic and ART-Suppressed Individuals.

Pathogens & immunity

Vásquez JJ, Aguilar-Rodriguez BL, Rodriguez L, Hogan LE, Somsouk M, McCune JM, Deeks SG, Laszik ZG, Hunt PW, Henrich TJ

Gene signatures common to allograft rejection are associated with lymphocytic bronchitis.

Clinical transplantation

Greenland JR, Wang P, Brotman JJ, Ahuja R, Chong TA, Kleinhenz ME, Leard LE, Golden JA, Hays SR, Kukreja J, Singer JP, Rajalingam R, Jones K, Laszik ZG, Trivedi NN, Greenland NY, Blanc PD

Expression of programmed cell death ligand 1 and programmed cell death 1 in cutaneous warts.

Journal of the American Academy of Dermatology

Yu WY, Berger TG, North JP, Laszik Z, Cohen JN

Identifying a potential biomarker for primary focal segmental glomerulosclerosis and its association with recurrence after transplantation.

Clinical transplantation

Harel E, Shoji J, Abraham V, Miller L, Laszik Z, Thurison T, King A, Olshen A, Leung J, Szabo G, Hann B, Høyer-Hansen G, Craik CS, Vincenti F

Severe Renal Allograft Rejection Resulting from Lenalidomide Therapy for Multiple Myeloma: Case Report.

Transplantation proceedings

Walavalkar V, Adey DB, Laszik ZG, Jen KY

Elucidating the Burden of HIV in Tissues Using Multiplexed Immunofluorescence and In Situ Hybridization: Methods for the Single-Cell Phenotypic Characterization of Cells Harboring HIV In Situ.

The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society

Vasquez JJ, Hussien R, Aguilar-Rodriguez B, Junger H, Dobi D, Henrich TJ, Thanh C, Gibson E, Hogan LE, McCune J, Hunt PW, Stoddart CA, Laszik ZG

Targeted Transcriptional Profiling of Kidney Transplant Biopsies.

Kidney international reports

Sigdel TK, Nguyen M, Dobi D, Hsieh SC, Liberto JM, Vincenti F, Sarwal MM, Laszik Z

Polyclonal Regulatory T Cell Therapy for Control of Inflammation in Kidney Transplants.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Chandran S, Tang Q, Sarwal M, Laszik ZG, Putnam AL, Lee K, Leung J, Nguyen V, Sigdel T, Tavares EC, Yang JYC, Hellerstein M, Fitch M, Bluestone JA, Vincenti F

Pilot Study of Renal Diffusion Tensor Imaging as a Correlate to Histopathology in Pediatric Renal Allografts.

AJR. American journal of roentgenology

Li Y, Lee MM, Worters PW, MacKenzie JD, Laszik Z, Courtier JL

Commensal Microbes and Hair Follicle Morphogenesis Coordinately Drive Treg Migration into Neonatal Skin.

Cell host & microbe

Scharschmidt TC, Vasquez KS, Pauli ML, Leitner EG, Chu K, Truong HA, Lowe MM, Sanchez Rodriguez R, Ali N, Laszik ZG, Sonnenburg JL, Millar SE, Rosenblum MD

Mycobacterium bovis Enterocolitis in an Immunocompromised Host.

Journal of pediatric gastroenterology and nutrition

Winger BA, Foy E, Sud SR, MacKenzie JD, Pua HH, Lau AH, Heyman MB, Laszik Z, Tureen J

Morphologic Features and Clinical Impact of Arteritis Concurrent with Transplant Glomerulopathy.

Pathology oncology research : POR

Dobi D, Bodó Z, Kemény É, Boda K, Szenohradszky P, Szederkényi E, Laszik ZG, Iványi B

Monoclonal light chain deposits within the stomach manifesting as immunotactoid gastropathy.

Ultrastructural pathology

Jen KY, Fix OK, Foster EN, Laszik ZG, Ferrell LD

Recurrent HIV-associated immune complex glomerulonephritis with lupus-like features after kidney transplantation.

American journal of kidney diseases : the official journal of the National Kidney Foundation

Chandran S, Jen KY, Laszik ZG

A study of interobserver reproducibility of morphologic lesions of focal segmental glomerulosclerosis.

Virchows Archiv : an international journal of pathology

Meehan SM, Chang A, Gibson IW, Kim L, Kambham N, Laszik Z

Reliability of whole slide images as a diagnostic modality for renal allograft biopsies.

Human pathology

Jen KY, Olson JL, Brodsky S, Zhou XJ, Nadasdy T, Laszik ZG

C4d/CD34 double-immunofluorescence staining of renal allograft biopsies for assessing peritubular capillary C4d positivity.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc

Jen KY, Nguyen TB, Vincenti FG, Laszik ZG

Cytomegalovirus in the transplanted kidney: a report of two cases and review of prophylaxis.

NDT plus

Anand S, Yabu JM, Melcher ML, Kambham N, Laszik Z, Tan JC

Kidney microvasculature in health and disease.

Contributions to nephrology

Jen KY, Haragsim L, Laszik ZG

Tamm-horsfall protein protects against urinary tract infection by proteus mirabilis.

The Journal of urology

Raffi HS, Bates JM, Laszik Z, Kumar S

Tamm-Horsfall protein knockout mice have increased stress induced micturition.

Neurourology and urodynamics

Raffi H, Bates J, Kumar S, Laszik Z, Buffington CA

The effect of costimulatory and interleukin 2 receptor blockade on regulatory T cells in renal transplantation.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Bluestone JA, Liu W, Yabu JM, Laszik ZG, Putnam A, Belingheri M, Gross DM, Townsend RM, Vincenti F

Human tumor antigens Tn and sialyl Tn arise from mutations in Cosmc.

Cancer research

Ju T, Lanneau GS, Gautam T, Wang Y, Xia B, Stowell SR, Willard MT, Wang W, Xia JY, Zuna RE, Laszik Z, Benbrook DM, Hanigan MH, Cummings RD

Thrombotic microangiopathy after allogeneic hematopoietic stem cell transplantation: an autopsy study.

Transplantation

Siami K, Kojouri K, Swisher KK, Selby GB, George JN, Laszik ZG

Infective endocarditis of a papillary fibroelastoma on Chiari network of right atrium: a case report.

Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography

Latif F, Peyton M, Laszik Z, Sivaram CA

HIV-associated nephropathy.

Advances in chronic kidney disease

Khan S, Haragsim L, Laszik ZG

Tamm-Horsfall protein knockout mice do not develop medullary cystic kidney disease.

Kidney international

Raffi H, Bates JM, Laszik Z, Kumar S

Chronic allograft nephropathy.

Advances in chronic kidney disease

Baluja P, Haragsim L, Laszik Z

Mesothelin is overexpressed in pancreaticobiliary adenocarcinomas but not in normal pancreas and chronic pancreatitis.

American journal of clinical pathology

Hassan R, Laszik ZG, Lerner M, Raffeld M, Postier R, Brackett D

Tamm-Horsfall protein acts as a general host-defense factor against bacterial cystitis.

American journal of nephrology

Raffi HS, Bates JM, Laszik Z, Kumar S

The protein C system in placental massive perivillous fibrin deposition.

Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis

Svensson AM, Waters BL, Laszik ZG, Simmons-Arnold L, Goodwin A, Beatty BG, Bovill EG

Laser-assisted microdissection of the kidney: fundamentals and applications.

Journal of molecular histology

Blakey GL, Laszik ZG

Tamm-Horsfall protein knockout mice are more prone to urinary tract infection: rapid communication.

Kidney international

Bates JM, Raffi HM, Prasadan K, Mascarenhas R, Laszik Z, Maeda N, Hultgren SJ, Kumar S

Searching for a valid animal model of hemolytic uremic syndrome.

American journal of clinical pathology

Laszik ZG, Blakey GL

Nitric oxide synthase expression in hypertension induced by inhibition of glutathione synthase.

The Journal of pharmacology and experimental therapeutics

Zhou XJ, Vaziri ND, Wang XQ, Silva FG, Laszik Z

Down-regulation of endothelial expression of endothelial cell protein C receptor and thrombomodulin in coronary atherosclerosis.

The American journal of pathology

Laszik ZG, Zhou XJ, Ferrell GL, Silva FG, Esmon CT

Outcome of renal transplantation in fibrillary glomerulonephritis.

Clinical nephrology

Samaniego M, Nadasdy GM, Laszik Z, Nadasdy T

Association of renal injury with increased oxygen free radical activity and altered nitric oxide metabolism in chronic experimental hemosiderosis.

Laboratory investigation; a journal of technical methods and pathology

Zhou XJ, Laszik Z, Wang XQ, Silva FG, Vaziri ND

Down-regulation of renal endothelial nitric oxide synthase expression in experimental glomerular thrombotic microangiopathy.

Laboratory investigation; a journal of technical methods and pathology

Zhou XJ, Laszik Z, Ni Z, Wang XQ, Brackett DJ, Lerner MR, Silva FG, Vaziri ND

The endothelial cell protein C receptor aids in host defense against Escherichia coli sepsis.

Blood

Taylor FB, Stearns-Kurosawa DJ, Kurosawa S, Ferrell G, Chang AC, Laszik Z, Kosanke S, Peer G, Esmon CT

Divergent inducible expression of P-selectin and E-selectin in mice and primates.

Blood

Yao L, Setiadi H, Xia L, Laszik Z, Taylor FB, McEver RP

MDC-L, a novel metalloprotease disintegrin cysteine-rich protein family member expressed by human lymphocytes.

The Journal of biological chemistry

Roberts CM, Tani PH, Bridges LC, Laszik Z, Bowditch RD

Endothelial protein C receptor.

Thrombosis and haemostasis

Esmon CT, Xu J, Gu JM, Qu D, Laszik Z, Ferrell G, Stearns-Kurosawa DJ, Kurosawa S, Taylor FB, Esmon NL

Cell proliferation in the developing human kidney.

Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society

Nadasdy T, Lajoie G, Laszik Z, Blick KE, Molnar-Nadasdy G, Silva FG

Tissue factor expression in mesothelial cells: induction both in vivo and in vitro.

American journal of respiratory cell and molecular biology

Bottles KD, Laszik Z, Morrissey JH, Kinasewitz GT

The protein C pathway: new insights.

Thrombosis and haemostasis

Esmon CT, Ding W, Yasuhiro K, Gu JM, Ferrell G, Regan LM, Stearns-Kurosawa DJ, Kurosawa S, Mather T, Laszik Z, Esmon NL

Mast cells in acute cellular rejection of human renal allografts.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc

Lajoie G, Nadasdy T, Laszik Z, Blick KE, Silva FG

Human acute tubular necrosis: a lectin and immunohistochemical study.

Human pathology

Nadasdy T, Laszik Z, Blick KE, Johnson DL, Burst-Singer K, Nast C, Cohen AH, Ormos J, Silva FG

Proliferative activity of cyst epithelium in human renal cystic diseases.

Journal of the American Society of Nephrology : JASN

Nadasdy T, Laszik Z, Lajoie G, Blick KE, Wheeler DE, Silva FG

The renal-cardiac connection: renal parenchymal alterations in patients with heart disease.

Seminars in nephrology

Lajoie G, Laszik Z, Nadasdy T, Silva FG

Renal interleukin-1 expression during endotoxemia and gram-negative septicemia in conscious rats.

Circulatory shock

Laszik Z, Nadasdy T, Johnson LD, Lerner MR, Brackett D, Silva FG

Lack of suppressed renal thrombomodulin expression in a septic rat model with glomerular thrombotic microangiopathy.

Laboratory investigation; a journal of technical methods and pathology

Laszik Z, Carson CW, Nadasdy T, Johnson LD, Lerner MR, Brackett DJ, Esmon CT, Silva FG

Proliferative activity of intrinsic cell populations in the normal human kidney.

Journal of the American Society of Nephrology : JASN

Nadasdy T, Laszik Z, Blick KE, Johnson LD, Silva FG

Absence of association between cytomegalovirus infection and obliterative transplant arteriopathy in renal allograft rejection.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc

Nadasdy T, Smith J, Laszik Z, Waner JL, Johnson LD, Silva FG

Tubular atrophy in the end-stage kidney: a lectin and immunohistochemical study.

Human pathology

Nadasdy T, Laszik Z, Blick KE, Johnson DL, Silva FG

Immunohistochemical and lectin dissection of the human nephron in health and disease.

Archives of pathology & laboratory medicine

Silva FG, Nadasdy T, Laszik Z

The role of the complement system in the pathogenesis of multiple organ failure in shock.

Progress in clinical and biological research

Zimmermann T, Laszik Z, Nagy S, Kaszaki J, Joo F